Figure3: Immunofluorescence analysis of K562 cells using anti-CD247 mAb (green). Blue: DRAQ5 fluorescent DNA dye.
	Flow cytometric analysis of Jurkat cells using anti-CD247 mAb (green) and negative control (purple).
	Immunohistochemical analysis of paraffin-embedded human Thymus tissues using anti-CD247 mouse mAb

The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.