PARP Mouse Monoclonal Antibody

货号: BD-PA0016
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规格 价格 期货 数量
  • 50μl
    1400.00
    3个工作日
    100μl
    2500.00
    3个工作日

产品基本信息

图片

Western blot analysis using PARP mouse mAb against Jurkat (1), K562 (2), Hela (3), Raji (4),THP-1 (5) and SW620 (6) cell lysate.
Flow cytometric analysis of Jurkat cells using anti-PARP mAb (green) and negative control (purple).

产品详情

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

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